The BRANDplates Insert System, co-developed with the Fraunhofer Society, is an innovative microplate system for cell culture applications such as co-culture, migration/invasion assays, and in vitro preparation of 3D tissue models. The system consists of two types of cell culture plates and a selection of cell culture inserts. The 24-well standard model is used in such applications as co-culture, migration/invasion assays, and chemotaxis assays, while the specialized 6-well model is well-suited for the automated in vitro preparation of human tissues (3D tissue culture). Key features to consider when selecting which components to use are plate selection and well size, insert type, and membrane pore size and material.
Inserts are available either smooth-walled or with special inlet channels (the Inlet Opening System*). The smooth-walled inserts are well-suited for standard applications such as secretion studies, co-culture, and chemotaxis studies. The Inlet Opening System enables rapid, consistent changing of media, from submersion culture to air-lift culture. The special inlet channels also enable adjustment of the medium level without damage to the tissue model. Inserts are also available with either PC (translucent) or PET (transparent) membranes for different optical requirements and cell visiblity, and in multiple membrane pore sizes for different applications. Through the many possible combinations of the Insert System you can respond flexibly to the different experimental needs and create perfect culture conditions.